@liefefenno @drglennsullivan @TheBorisLab Perhaps we are misinterpreting that naltrexone/ketamine paper. It’s not that ketamine works through opioids, it’s that blocking them decreases the placebo effect? More to learn here. https://t.co/2U3E2oL1Vw
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism https://t.co/2XOC0hfOA2
@psychwrite Or the opioid effect of ketamine for efficacy?? https://t.co/AopTblMSOb
@IlanaWitten @sohallab @TheresaLii Rodent models for ket are a challenge 😁. Did a trial w @NolanRyWilliams a few yrs ago showing ketamine's antidep effect requires opioid receptors. standard rodent assays don't capture that human finding well, cautious re
RT @leoschilbach: Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://…
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.co/yb2sH0FAHZ
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
So the question is, what are these opiate replacement meds doing to peoples psyche?
RT @drrickbarnett: Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects an…
Well, this i did not know and surprised i did not learn it sooner. Naltrexone blocks ketamine anti-depressant effects and findings “suggest that ketamine’s acute antidepressant effect requires opioid system activation” 1/ https://t.co/6YombELNXW
Exploring potential in using psychedelics to treat depression but without the intoxicating effects. "Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism". #Mentalhealth #depression #psychedelics #research #ketamine https://t.co/
RT @roscoebradyjr: @TheBorisLab I’m really excited to see this when it’s written up! Also: Drawing a thread between this and your earlier w…
@TheBorisLab I’m really excited to see this when it’s written up! Also: Drawing a thread between this and your earlier work: https://t.co/pa3yxDWSc1 ..do you think naloxone blocked a placebo effect in that study?
Handful of studies showing opioid antagonism decreases antidepressant effects of ketamine (“opioid system is necessary but not sufficient for antidepressive actions of ketamine”) https://t.co/BUGaluJ1jW https://t.co/fGi7Pnfwc8
@rkayama @sakazume1965 そのような「BDNF作用薬」の有効性が特別大きいわけではありません。むしろ少し小さいくらいです。登場したと同時に「否定的」と結論づけられた「#BDNF仮説」 https://t.co/fdOvirdA74
RT @MdParangi: Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.c…
RT @abrahamnunes: Ketamine's action in depression might not be through NMDAR, but may involve opioid receptors. Orange: Ketamine+Naltrexo…
RT @Altostrata: Yep, this is a replay of the fad for the new #antidepressants. Eventually, it’s going to be “we don’t know how ketamine wor…
RT @Altostrata: Yep, this is a replay of the fad for the new #antidepressants. Eventually, it’s going to be “we don’t know how ketamine wor…
Yep, this is a replay of the fad for the new #antidepressants. Eventually, it’s going to be “we don’t know how ketamine works for depression, we just strongly believe it works”.
Ketamine's action in depression might not be through NMDAR, but may involve opioid receptors. Orange: Ketamine+Naltrexone Green: Ketamine+Placebo Data are in ketamine responders. https://t.co/bAKIngrOR9 https://t.co/oikYLC1LdH
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.co/DFr62M59mz
@awaisaftab https://t.co/f35jx6SsIe Had Dr Nolan for grand rounds last year, association of opioid antagonism and ketamines antidepressant effects was interesting.
@ArgelAV @ramthescientist Maybe related, here's study in humans showing that mu-opioid block abolishes ketamine's antidepressant effect: https://t.co/zmbo0ZiEeJ
@zenbrainest @PennAnesthesia Whatever is happening, ketamine is not morphine... but an enormous amt of clinical evidence suggests ketamine modulates the opioid system eg modying opioid response, https://t.co/JPHQNivnKN (and our smaller scale study https://
@rogelioramost75 @drlangosta @JRBneuropsiq @dranibalacosta @drbernardong Aún no se ha replicado este estudio https://t.co/7FcTD95ypN
RT @TheBorisLab: @MichaelBritoUM Our own work with ketamine vs ketamine/naltrexone ... ?dissociate dissociation? from therapeutic fx https:…
@MichaelBritoUM Our own work with ketamine vs ketamine/naltrexone ... ?dissociate dissociation? from therapeutic fx https://t.co/kTsIXkn5FA not to mention the prelim open label of R-ket which seems therapeutic with limited dissociative fx https://t.co/8AUm
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism https://t.co/fyODrA4L3R
RT @artwalaszek: @awaisaftab The ad also forgets to mention that the antidepressant activity of ketamine may be due in part to opioid recep…
@awaisaftab The ad also forgets to mention that the antidepressant activity of ketamine may be due in part to opioid receptor activity. https://t.co/O8k6EFnYOM
Preliminary data showing that the antidepressant effect of #ketamine is blocked by naltrexone, while the consciousness-altering effect is not. The consciousness-alteration may not be necessary for clinical utility. Relevant to other #psychedelics? https:
重度 #うつ病 患者に #ケタミン 静注すると翌日に #HAMD が平均5点まで改善することが示されている。それは #EffectSize > 2.0 となる。
Not the point of the story but turns out she was an author on this ketamine for depression paper too! https://t.co/x213VC1R4y
from 2018 https://t.co/RD9T0l2n96
Attenuation of Antidepressant Effects of #Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.co/O9GYm2U2m0 #depression #chronicpain #anesthesia
Ketamine doesn't work for depression if opioid system is blunted: https://t.co/K5cG35Z277
Ketamina como tto de la depresión. La ketamina es nuestra aspirina anestesica. Alta eficacia en múltiples aplicaciones https://t.co/HHfv1qdNdx
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism https://t.co/T1puAHYa3W #aaap30
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism https://t.co/T1puAHYa3W
RT @Jetlax: @Wal_Yas @DrHowardLiu @IRCN_UTokyo How could this tie in with one particular small trial last year, where administration of nal…
@Wal_Yas @DrHowardLiu @IRCN_UTokyo How could this tie in with one particular small trial last year, where administration of naltrexone prior to the ketamine infusion blocked the antidepressant but not the dissociative effect of ketamine? https://t.co/vhbi
https://t.co/fgxtk1qPQ8 Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism. Williams NR, et al. Am J Psychiatry. 2018.
Christine Blasey Ford recently published an AJP paper showing that opiate receptor activity is necessary for ketamine’s anti-depressant effects. https://t.co/dK33csjxiz
RT @APA_Publishing: #Opioid receptors are implicated in ketamine’s acute antidepressant effects in adults w/ treatment-resistant #depressio…
RT @APA_Publishing: #Opioid receptors are implicated in ketamine’s acute antidepressant effects in adults w/ treatment-resistant #depressio…
RT @NDEWSNews: Until now, researchers have linked #ketamine to its effect on the glutamate system in the brain. New findings suggest that k…
@HengartnerMP And don't forget that already hyped ketamine actually works through opiod receptors (because ofcourse:)) https://t.co/zMfKhpSLNl
RT @UpdateonScience: https://t.co/aRP6MZ4ynj Antidepressant effects of ketamine greatly reduced in patients also taking naltrexone in a dou…
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism. - PubMed - NCBI https://t.co/09h4oMqCtI
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism. - https://t.co/8BZX10Sqos
https://t.co/aRP6MZ4ynj Antidepressant effects of ketamine greatly reduced in patients also taking naltrexone in a double-blind crossover study of 30 adults with treatment-resistant depression. #sciencenews https://t.co/q0nAaATrE9
@pitiklinov Es el segundo estudio que veo en esta línea https://t.co/JD7fatpQ7J
RT @APA_Publishing: #Opioid receptors are implicated in ketamine’s acute antidepressant effects in adults w/ treatment-resistant #depressio…
RT @StanfordPSY: .@StanfordPSY researchers have found that ketamine's antidepressive effects are tied to the brain's opioid system. The muc…
RT @StanfordPSY: Here's the @StanfordPSY ketamine study everyone's been talking about! https://t.co/kJxvsdTVa5 <-- As published in @AmJPsyc…
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.co/NAQicZzNg0
Spent some time reviewing this paper from August in @AmJPsychiatry about ketamine and opioid system activation. Look at that authors list! https://t.co/zpRTq29POO https://t.co/Cb8vJOz8FQ
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.co/hZPuG7L2Xq
https://t.co/Iau1NEZgDD researchAttenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.co/de4lEvjHZo
RT @BellevueDoc: turns out Dr. Blasey-Ford's most recent publication was a much respected ketamine article in American Journal of Psychiatr…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @BellevueDoc: turns out Dr. Blasey-Ford's most recent publication was a much respected ketamine article in American Journal of Psychiatr…
RT @BellevueDoc: turns out Dr. Blasey-Ford's most recent publication was a much respected ketamine article in American Journal of Psychiatr…
blasey ford + ketamine in case there was any doubt she’s legit https://t.co/vdhA1oCkQI
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @GarrettReuscher: Not only is Dr. Ford an American hero but also published study on ketamine’s effect on depression: Attenuation of Ant…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
Not only is Dr. Ford an American hero but also published study on ketamine’s effect on depression: Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism | American Journal of Psychiatry https://t.co/d9AL7VV1mu
RT @BellevueDoc: turns out Dr. Blasey-Ford's most recent publication was a much respected ketamine article in American Journal of Psychiatr…
RT @BellevueDoc: turns out Dr. Blasey-Ford's most recent publication was a much respected ketamine article in American Journal of Psychiatr…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
Wow! This is something. Go, Dr. Ford!
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…
RT @MyHarmReduction: Hey #harmreduction fam, apparently Dr. Blasey-Ford is one of us- she published on ketamine for depression! Nice find,…